Check this mouse out, pointed out to me by my old WoW Guildmate, Evil Monkey.
It's a custom made mouse for World Of Warcraft with a mega arse-ton of buttons and options.
And here's the configuration software for it. It even has the same look as the game. Pretty slick.
It says some of it's features are:
- Program all 15 buttons with over 130 preset game commands
- Create custom macros (supports in-game macros)
- Develop up to 10 profiles, each with a unique illumination scheme
- Choose from 16 million colors, all with 4 levels of intensity and pulsation
- 3200 Max DPI (wow)
Full info can be found on it's page.
If I didn't already have a new Logitech MX518, (love it) I'd probably pick this bad boy up. Just make sure to hide it when any chicks walk in. 
You can get it from here or here
.