When shopping for a new computer its really is determined on that purpose you plan to use it for. Really there is no right or wrong answer but more of what are you looking for in it? What are your expectations in it?
If your looking for one on the go and you don't want to really haul it around in a laptop bag then a netbook may be the way to go they are much smaller and can be tossed in alot of purses or in a brief case (if traveling for work). However with a netbook you are limited on hard drive room, no DVD player along with the size can be a issue (good or bad). Now if your looking to really only surf the web, read your email and update your social site then they are awesome. Plus the bonus of the lower price is nice. For on the go and travel they are great.
Now if your looking for a computer at home then no I would stay away from a netbook as it does limit you. With a notebook they are much larger, they have better processors, you get the DVD drive and generally more ram and a larger hard drive. They also have larger keyboards and if you have ever typed on a netbook you will soon learn that its harder since everything is crammed and generally the audio is much better in the Notebooks. Yes they are more money and no you can't simply toss it in your purse or brief case.
So really its a matter of what you are looking for. One think I would recommend is visiting a site like officedepot.com where you can select a few different ones and do a side by side comparison. Here on Office Depot I compared two different ones, the HP Mini 110-1030NR XP Edition 10.1" Widescreen Netbook Computer VS the HP G60-440US 16" Widescreen Notebook Computer and you can see the results here:
Intel Insider Frank Gruber also did a youtube video comparing two of them (the volume is real low so you have to turn it way up to hear him talk):
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